| Date | Opponent | Location | Time |
| Feb. 7 | Austin College (2) L, 6-2 (0-1, 0-0 ASC) W, 10-0 (1-1, 0-0 ASC) | Seguin, Texas | Noon |
| Feb. 8 | Austin College (1) W, 4-3 (2-1, 0-0 ASC) | Seguin, Texas | Noon |
| Feb. 10 | Trinity (1) W, 7-3 (3-1, 0-0 ASC) | Seguin, Texas | 2 p.m. |
| Feb. 13 | Cal State - Eastbay (1) L, 9-1 (3-2, 0-0 ASC) | Seguin, Texas | 2 p.m. |
| Feb. 14 | Cal State - Eastbay (1) W, 6-2 (4-2, 0-0 ASC) | Seguin, Texas | 1 p.m. |
| Feb. 15 | Cal State - Eastbay (1) W, 7-5 (5-2, 0-0 ASC) | Seguin, Texas | Noon |
| Feb. 17 | Southwestern (1) W, 14-6 (6-2, 0-0 ASC) | Seguin, Texas | 2 p.m. |
| Feb. 20 | at Univ. of Texas-Dallas (1) L, 13-6 (6-3, 0-0 ASC) | Richardson, Texas | 2 p.m. |
| Feb. 21 | at Univ. of Texas-Dallas (2) L, 14-13 (6-4, 0-0 ASC) L, 10-9 (6-5, 0-0 ASC) | Richardson, Texas | Noon |
| Feb. 27 | Mississippi College (1) W, 15-12 (7-5, 0-0 ASC) | Seguin, Texas | 2 p.m. |
| Feb. 28 | Mississippi College (2) W, 17-7 (8-5, 0-0 ASC) W, 19-12 (9-5, 0-0 ASC) | Seguin, Texas | Noon |
| March 4 | DeSales (1) W, 20-3 (10-5, 0-0 ASC) | Seguin, Texas | 2 p.m. |
| March 6 | Concordia Texas (1)* W, 3-2 (11-5, 1-0 ASC) | Seguin, Texas | 2 p.m. |
| March 7 | Concordia Texas (2)* W, 2-1 (12-5, 2-0 ASC) L, 3-2 (12-6, 2-1 ASC) | Seguin, Texas | Noon |
| March 9 | Wabash (1) L, 6-0 (12-7, 2-1 ASC) | Seguin, Texas | 2 p.m. |
| March 10 | Concordia Nebraska (1) W, 4-3 (13-7, 2-1 ASC) | Seguin, Texas | 1 p.m. |
| March 14 | at McMurry (1)* (date/time change) W, 9-8 (14-7, 3-1 ASC) | Abilene, Texas | 7 p.m. |
| March 15 | at McMurry (2)* (date/time change) L, 3-2 (14-8, 3-2 ASC) L, 3-1 (14-9, 3-3 ASC) | Abilene, Texas | Noon |
| March 20 | at Howard Payne (1)* W, 8-7 (15-9, 4-3 ASC) | Brownwood, Texas | 2 p.m. |
| March 21 | at Howard Payne (2)* W, 13-3 (16-9, 5-3 ASC) W, 16-8 (17-9, 6-3 ASC) | Brownwood, Texas | 1 p.m. |
| March 24 | at Trinity (1) L, 14-6 (17-10, 6-3 ASC) | San Antonio, Texas | 7 p.m. |
| March 27 | Mary Hardin-Baylor (1)* W, 6-4 (18-10, 7-3 ASC) | Seguin, Texas | 2 p.m. |
| March 28 | Mary Hardin-Baylor (2)* W, 13-4 (19-10, 8-3 ASC) L, 15-14 (19-11, 8-4 ASC) | Seguin, Texas | Noon |
| April 3 | at Sul Ross State (1)* W, 13-0 (20-11, 9-4 ASC) | Alpine, Texas | 7 p.m. |
| April 4 | at Sul Ross State (2)* W, 8-5 (21-11, 10-4 ASC) W, 9-2 (22-11, 11-4 ASC) | Alpine, Texas | Noon |
| April 7 | at Southwestern (1) W, 5-3 (23-11, 11-4 ASC) | Georgetown, Texas | 5 p.m. |
| April 9 | Schreiner (1)* W, 19-8 (24-11, 12-4 ASC) | Seguin, Texas | 2 p.m. |
| April 10 | Schreiner (2)* W, 13-6 (25-11, 13-4 ASC) W, 10-0 (26-11, 14-4 ASC) | Seguin, Texas | 1 p.m. |
| April 17 | at Hardin-Simmons (1)* W, 19-11 (27-11, 15-4 ASC) | Abilene, Texas | 7 p.m. |
| April 18 | at Hardin-Simmons (2)* L, 8-2 (27-12, 15-5 ASC) W, 4-1 (28-12, 16-5 ASC) | Abilene, Texas | 1 p.m. |
| April 24 | First Round of ASC Championship Tournament Best 2-of-3 Series TLU hosts University of the Ozarks (Ark.) TLU 10, Ozarks 1 (29-12, 16-5 ASC) | Seguin, Texas | 2 p.m. |
| April 25 | First Round of ASC Championship Tournament Best 2-of-3 Series TLU v. University of the Ozarks (Ark.) (Game 2 at 11 a.m. / Game 3, if necessary, 30 minutes after Game 2) TLU 2, Ozarks 0 (30-12, 16-5 ASC) | Seguin, Texas | 11 a.m. |
| May 1 | ASC Championship Tournament Championship Round Double-Elimination UT-Tyler 7, Texas Lutheran 6 (30-13, 16-5 ASC) Tournament Bracket Listen Live Live Stats | Clinton, Miss. | 3 p.m. |
| May 2 | ASC Championship Tournament Championship Round Double-Elimination TLU vs. UT-Dallas / Mississippi College Tournament Bracket Listen Live Live Stats | Clinton, Miss. | Noon |
| May 3 | ASC Championship Tournament Championship Round Double-Elimination TLU vs. TBA Tournament Bracket Listen Live Live Stats | Clinton, Miss. | TBA |
| May 13-16 | NCAA West Regional Championships | McMinnville, Ore. (Linfield College) | TBA |
| May 22-26 | NCAA DIII Championship Tournament | TBD | TBA |